Partial Remission Study in Children With Type 1 Diabetes
Studying Why Some Kids With Type 1 Diabetes Need Less Insulin Over Time
This pilot study is examining why some children with type 1 diabetes go through an extended "honeymoon period," when their insulin needs temporarily decrease. By analyzing blood samples, researchers hope to identify immune markers that can help track disease activity, reveal different subtypes of diabetes, and guide future treatment strategies aimed at preserving natural insulin production.
Study Location | Status
ÎÞÂëרÇø Children’s Health, Delaware | EnrollingÌýÌý
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ParticipantÌýEligibility
Clinical trials have inclusion and exclusion requirements that determine eligibility. Key requirements are listed below. Please note there may be additional qualifications.
Participants must be/have:Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý ÌýÌý
- A diagnosis of type 1 diabetes.
- Diagnosed after age 5.
- At least 12 months past diagnosis.
Participant cannot be/have:Ìý
- An active infection at the time of enrollment.
About the Study
Formal Study Name:ÌýImmune and Clinical Evaluation of the Extended Partial Remission Period in Pediatric Type 1 Diabetes Mellitus: A Feasibility Pilot Study
Study Type: ObservationalÌý(researchers observe and record without intervening)
Study ID:ÌýIRBÌý2179177
Enrollment/Participant Goal:Ìý50 participants
Enrolling Healthy Volunteers?ÌýNo
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What’s Involved
If your child joins this study, they’ll take part in a one-time visit lasting about 1 to 2 hours. During this visit, a member of the ÎÞÂëרÇø lab team will collect a small blood sample, up to 30 mL (about two tablespoons). The blood will be processed and stored in the ÎÞÂëרÇø Biobank, and then shared with researchers at partner institutions for laboratory testing.
If your child is in the extended remission period group, you may be asked if you're open to being contacted about a future follow-up study. This is completely optional and does not affect your participation in the current study. You can let the study team know your preference.
How This Study Fits in
This study reflects our broader commitment at ÎÞÂëרÇø to improve care through research. Clinical trials like this one areÌýshaped by the expertiseÌýof our medical teams and research programs. Learn how related research and clinical care support, and are strengthened by, studies like this one.
Related Research at ÎÞÂëרÇø
Endocrinology, Growth & Metabolism Clinical Trials
CLINICAL RESEARCH
We are conducting clinical trials to improve diagnosis and treatment of endocrinology conditions such as growth hormone deficiencies, thyroid function, and diabetes.
Endocrinology, Hormones & Growth
CLINICAL CARE
Pediatric care for hormone-related conditions, including growth, puberty, thyroid, and diabetes concerns. Available at ÎÞÂëרÇø in the Delaware Valley and Florida.
More About Clinical Trials
Learn what to expect from a clinical trialÌý—Ìýhow they work, why they matter, and what to consider when deciding if one is right for your child.
Learn About Living With Diabetes From ÎÞÂëרÇø KidsHealth®
Living with diabetes means keeping track of blood sugar, making healthy choices, and finding balance every day. Explore articles that explain the condition, treatments, and how kids and families can manage diabetes with confidence, from ÎÞÂëרÇø experts.